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I-LONGEVITY Protocol: Anti Aging Guide to Help People Prevent and Reverse Aging (2025)

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Contents Methodology What is Aging? Biological Age vs Chronological Age Causes of Aging and Hallmarks of Aging What is Cell Senescence? What is Epigenetics? Diet and Lifestyle for Anti Aging Avoiding Sugar and Ultra-processed Foods Mediterranean Diet and Vegetables Avoiding Smoking and Alcohol Stress Management Avoiding Linoleic Acid (Omega-6 Fatty Acids) and Vegetable Oil Exercise, Resistance Training and Walking Sleep Social Support Caloric Restriction, Intermittent fasting (Time Restricted Eating) and Fasting Best Scientifically Proven Anti Aging Supplements Vitamin D3 and K2 Glycine, NAC and Taurine B Vitamins, Nicotinamide mononucleotide (NMN) and NAD Boosting Supplements Omega-3 fatty acids Magnesium and Molecular Hydrogen Curcumin (Turmeric) Vitamin C CoQ10 Zinc EGCG (Green Tea) Lutein and Zeaxanthin Glucosamine and Chondroitin Protein Powder and Collagen Spermidine Crocin (Saffron) Cocoa Creatine Melatonin Other Promising Interventions for Longevity Stem Cell Therapy for Anti-A...
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18 Best Supplements to Reduce Cytokine Storm: Advanced Guide

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As of May 2024, there are more than 4,000 early treatment studies  that have been published and shared with the whole world. New ones are being added every day.  This is a review of the literature, covering multiple observational studies, randomized controlled trials and references related to natural supplements and cytokine storm with more than 300 studies and references. We know that while a large percentage of the population only experiences mild to moderate symptoms of COVID-19 and won’t require hospitalization, others experience severe symptoms and complications, require hospitalization, or may even die.  It appears one of the differences between those who have a mild illness and severe illness is related to the body's ability to reduce the hyperimmune response that leads to a cytokine storm and the hyper-coagulability (tendency for blood clots) that often accompanies it. The cytokine storm may be one possible way to ex...
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NAC vs NAD vs NR vs NMN vs Niacin: What Are the Differences?

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NAC vs NAD vs Niacin vs NR vs NMN . Due to the small alphabetical differences, these supplements are often mixed up and confused by most consumers. We will cover the essentials and explain about each of these supplements below. Contents NAD NAD vs NAD+ NAD+ for Anti Aging NAD+ Helps Restore Age-Related Muscle Deterioration NAD and Resveratrol NAD Supplements NAC Niacin (NA) NR NMN NAC vs NMN Gluthatione vs NAC NAC vs Niacin NR vs NMN Can you take NR and NMN together? Niacin vs NR vs NMN Stability and Storage of NMN and NR Naturally Boosting NAD Levels Related Articles NAD NAD is a type of coenzyme found in all living cells. NAD plays important roles in a variety of metabolic reactions, including energy production and DNA repair. NAD is derived from Nicotinamide Riboside (NR) and various other precu...
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14 Best Baby Diapers of 2025 - Price, Reviews, Comparison

By Dr Frank Yap, MD
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  What Makes a Good Diaper? Babies go through a lot of wet and soiled diapers during those first few weeks. To prepare for this phenomenon, most parents build a stockpile of diapers before baby arrives. This can be an overwhelming task for both seasoned and first-time parents, and there are many factors to consider when stocking up, such as baby’s weight, diaper fit, and finances. a. Softness Baby skin is delicate and sensitive, especially during the newborn days. And your baby will have a diaper resting against their skin 24/7 for at least a few years. A good disposable should be made from materials that are as soft and comfortable as possible, both inside and out. b. Stretch Babies come in all different shapes and sizes. While you can’t fully control fit, a diaper that stretches to conform to the broadest range of babies’ weights and sizes offers the best chance of a good fit and, ultimately, ...
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Dr. Zelenko's Z-Stack Vitamin Cocktail: Review 2024

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The  Zelenko COVID-19 Protocols  was developed by Dr Vladimir Zelenko. The protocol has as its centerpiece, but not exclusive piece, the combined use of Hydroxychloroquine (HCQ) and Zinc as a means by which a person can both help to prevent or mitigate the contraction of  COVID-19 , or can actually treat the disease once it has been diagnosed.  A  retrospective study  analyzing Dr Zelenko's patient data was accepted for publication after a rigorous peer review process. The study finds that early intervention and treatment of high-risk patients with COVID-19 resulted in significantly fewer hospitalizations and deaths. The treatment consisting of zinc, low-dose hydroxychloroquine (HCQ), and azithromycin, is also referred to as "The Zelenko Protocol." Dr Zelenko has since updated his protocols to incorporate new evidence. He has since evolved his protocols to include a quercetin, zinc, vitamin D and C protocol for low-ris...
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12 Best Vitamin D3 Supplements of 2025

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Vitamin D is a fat-soluble vitamin, meaning that it dissolves in fats and oils and can be stored in your body for a long time. Two main dietary forms exist: Vitamin D3 (cholecalciferol). Found in some animal foods, like fatty fish and egg yolks. Vitamin D2 (ergocalciferol). Found in some plants, mushrooms, and yeasts. The Global Vitamin D Market size was worth US$ 1.1 billion in 2022 ( R ), and it is estimated to reach a valuation of US$ 1.7 billion by the end of 2028, expanding at an annual compound rate of 7.0% between 2023 and 2028. What is Vitamin D Good For? Vitamin D helps keep you bones strong by aiding in the absorption of calcium and phosphorus. It's involved in maintaining a healthy immune system, mood regulation, heart health, and even weight loss .  What is the Best Form of Vitamin D?  Vitamin D is a fat-soluble vitamin, meaning that it does not dissolve in water and is absorbed best in your bloodstre...
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9 Types of Zinc Supplementation and Absorption

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Zinc is a powerful immune nutrient known for its benefits for providing immune health support and inflammation reduction as well as for improving cold and respiratory symptoms, wound healing, acne reduction, and lowering the risk of age-related diseases. Research on atherosclerosis and diabetes mellitus suggests that zinc deficiency may contribute to low-grade systemic inflammation. Even more popular at the moment is the role of  zinc and the potential benefits against COVID-19 . This is probably one of the reasons that's driving the demand on zinc related products. In a  ConsumerLab survey  of 9,647 people who use dietary supplements shows that the supplements which experienced the greatest growth in popularity in 2020 were those being promoted to prevent or treat infection with SARS-CoV-2, the coronavirus that causes COVID-19. Zinc supplements achieved the highest growth with 13.5% points. Does zinc help treat COVID 19? In order to answer that question, there are many z...
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Exosomes vs PRP Therapy vs Stem Cells: What's the Difference? (2025 Edition)

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In these past few years, stem cells, PRP (platelet-rich plasma) and exosomes have been hot topics among researchers and doctors. However, these forms of treatments are often mixed up and are confusing for most average consumers.  As of February 2025, there are  more than 300,000 studies  related to "stem cell",  more than 30,000 studies  published related to exosome and  more than 14,000 studies  related to PRP on PubMed (US NIH Library of Medicine Database).  Nevertheless, stem cell, PRP and exosome-related therapies are not yet established as standard treatments, given their relatively recent emergence. Regenerative medicine is also becoming a buzzword in the medical community. Why? Because the human body is specially equipped to heal itself, and regenerative therapies tap into this powerful ability. Regenerative medicine includes treatments like stem cell therapy, exosome therapy and platelet-rich plasma (PRP) therapy. Res...
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10 Best NMN Supplements (2025 Review)

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NMN stands for nicotinamide mononucleotide and is a precursor to NAD+, or nicotinamide adenine dinucleotide. NMN is the direct precursor of the essential molecule nicotinamide adenine dinucleotide (NAD+) and is considered a key component to increase NAD+ levels in cells. NAD+ is a critical molecule found in every cell of your body, but levels of NAD+ naturally fall with age, making it — and NMN, as a result — crucial. NMN is one of the most popular supplements in the anti aging community. The global Nicotinamide Mononucleotide (NMN) market was valued at US$ 98.5 million in 2019 and it is expected to reach US$ 296.5 million ( R ) by the end of 2026, growing at a CAGR (Compound Annual Growth Rate) of 7.3% during 2021-2026. The NAD story took off toward the end of 2013 with a  high-profile paper  by Harvard's David Sinclair and colleagues. Sinclair, recall, achieved fame in the mid-2000s for research on yeast and mice that suggested the red wine ing...
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Vitamin D 25 Hydroxy and Vitamin D 1 25 Dihydroxy: What's the Difference?

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Vitamin D is more than just one vitamin. It’s a family of nutrients that shares similarities in chemical structure. Vitamin D helps your body absorb calcium and maintain strong bones throughout your entire life. Your body produces vitamin D when the sun’s UV rays contact your skin. Other good sources of the vitamin include fish, eggs, and fortified dairy products. It’s also available as a dietary supplement. In your diet, the most commonly found members are vitamin D2 and D3. While both types help you meet your vitamin D requirements, they differ in a few important ways. Research even suggests that vitamin D2 is less effective than vitamin D3 at raising blood levels of vitamin D. Dietary vitamin D comes in two main forms: Vitamin D2 (ergocalciferol) Vitamin D3 (cholecalciferol) The two forms of vitamin D differ depending on their food sources. Vitamin D3 is only found in animal-sourced foods, whereas D2 mainly comes from plant sources and fortified foods. Your skin makes vitamin D3 whe...
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